Fernando Pedro Cossio,Eneko Aldaba Arevalo,Yosu Ion Vara Salazar,Aizpea Zubia Olascoaga,Silvia Vivanco Amato,Miren Lorea Mendoza Arteche,Clarisa Salado Pogonza,Natalia Gallot Escobal,Fernando Vidal Va
申请号：
US12861581
公开号：
US08097656B2
申请日:
2010.08.23
申请国别(地区):
US
年份:
2012
代理人:
摘要：
This invention is related to new nitrogenated trans-stilbene compounds, more specifically, imine, pyrrole and indole derivatives, with procedures for the preparation and use thereof as pharmaceutical compositions for the treatment and/or chemoprevention of those mammalian diseases such as cancer, fibrosclerosis and acute/chronic inflammation, graft-versus-host reaction, ischemic-reperfusion tissue injury in stroke and heart attack, neurodegeneration, and during organ transplantation, whose pathogenic and pathophysiological mechanisms depend on or are significantly contributed by undesirable oxidative stress, angiogenic and proliferative responses.
