GENIN, MICHAEL JAMES,HOLLOWAY, WILLIAM GLEN,JOHNSTON, RICHARD DUANE,MORPHY, JOHN RICHARD,SHI, QING
申请号：
TW107124931
公开号：
TWI670271B
申请日:
2018.07.19
申请国别(地区):
TW
年份:
2019
代理人:
摘要：
The present invention provides a compound of Formula (I), wherein X is H or C1-C3 alkyl optionally substituted with hydroxyl； Y is H, hydroxy, or methyl； R is ethyl, n-propyl, cyclopropyl, or Formula (II)； and A is methyl, cyclopropyl or trifluorom ethyl； or a pharmaceutically acceptable salt thereof； with the proviso that when X and Y are both H and R is n-propyl, then A is other than methyl； for use as a human PDEl inhibitor.
