MANIPULATED NATURAL KILLER CELLS AND APPLICATIONS THEREOF

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专利权人:

Onkimmune Limited

发明人:

O'DWYER, Michael Eamon Peter

申请号：

DK17825774

公开号：

DK3454871T3

申请日:

2017.12.11

申请国别(地区):

DK

年份:

2019

代理人:

摘要：

Natural killer cells are modified to express chimeric antigen receptors (CARs) for CD38. The cells can contain other modifications that improve tumor specific cytotoxicity and homing to tumor sites, e.g. expression of mutant TRAIL. Methods for using the engineered natural killer cells, e.g. to treat patients with cancer, are provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/