KANNAN GUNASEKARAN,LAVALLEE JENNIFER,JACOBSEN FREDERICK W
申请号：
IN201617004102
公开号：
IN201617004102A
申请日:
2016.02.04
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
This disclosure provides polypeptides comprising an antibody Fc region having a deletion of one or more cysteine residues in the hinge region and substitution with a sulfhydryl containing residue of one or more CH3 inteface amino acids. Also provided are Fc fusion proteins and antibodies containing said polypeptides nucleic acids and vectors encoding said polypeptides along with host cells and methods for making said polypeptides.
