Bing Gong,Rachel Rennard,Amanda Frank Oliphant,Cheuk Lun Leung,Benjamin Jacob Wolf,Ugur Eskiocak,Pearl Bakhru,Diana I. Albu
申请号：
US16682756
公开号：
US20200181266A1
申请日:
2019.11.13
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present disclosure relates to compositions and methods for inhibiting tumor evasion by reducing immune checkpoint suppression. In some embodiments, provided herein are compositions that block the interaction between PD-1 and its ligand (e.g., PD-1 and/or PD-L2) while promoting the interaction of the cells on which PD-1 and its ligand are expressed. Also provided are methods of using such compositions.
