TENGLER, MARK,TASKEY, PAUL,LOCKHART, DANIEL,MCMAHEN, RUSSELL LEE
申请号:
EP06736077
公开号:
EP1855613A4
申请日:
2006.02.24
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The present invention includes compositions and methods for the controlled release of active agents in a shelf-stable liquid formulation by blending one or more controlled release microbeads comprising one or more active agents, preparing a dense, thixotropic solution having a density that is at, or about, the density of the one or more microbeads comprising a thixotropic agent, water and one or more preservatives under conditions that reduce bubble formation and mixing the microbeads and the thixotropic solutions in a mixer that lacks scraping paddles.