Purposes in the bright quinoline System Prepare Drug object for being related to replacing of this Hair, The Drug object controls Treatment insecticide tolerance Fen Zhi Rod bacterium Genus strain infection with what, and the quinoline that wherein The replaces is acceptable Suan Huo Alkaline Jia Cheng Which on formula (Ia) or formula (Ib) compound, Qi Drug Learn, Qi Li Bodyization Learn Iso Agencies form, its mutual Change Iso Agencies form and its N- oxide form. It Yaos Ke on Qiu Bao Nursing Han Drug Learn and receives Load Body, and controls a effective amount of above compound of Treatment He the other anti-Fen Zhi Rod bacterium Drug objects of Yi Seed Huo Duo Seed close object as active constituent Group.本發明涉及取代的喹啉衍生物在製備藥物中的用途，該藥物用於治療耐藥性分枝桿菌屬菌株感染，其中該取代的喹啉衍生物是式(Ia)或式(Ib)化合物、其藥學上可接受的酸或鹼加成鹽、其立體化學異構形式、其互變異構形式及其N-氧化物形式。還要求保護含藥學上可接受的載體，以及治療有效量的以上化合物和一種或多種其它抗分枝桿菌藥物作爲活性成分的組合物。
