An acupressure sleeve for applying acupressure to predetermined acupoints on an arm of a user includes a sleeve body and an acupressure unit. The sleeve body is configured to elastically and tightly press against the arm of the user when the acupressure sleeve is worn by the user. The sleeve body has a fiber substrate, and a plurality of far-infrared particles and a plurality of negative ion particles blended in the fiber substrate. The acupressure unit includes a plurality of acupressure protrusions protruding from the fiber substrate into an interior of the sleeve body and configured to apply acupressure to the arm of the user at positions respectively corresponding to the predetermined acupoints.
