PRASAD V. CHATURVEDULA,LING CHEN,RITA CIVIELLO,CHARLES MARK CONWAY,ANDREW P. DEGNAN,GENE M. DUBOWCHIK,XIAOJUN HAN,GEORGE N. KARAGEORGE,GUANGLIN LUO,GRAHAM POINDEXTER,JOHN E. MACOR,SHIKHA VIG
申请号：
PT03736721
公开号：
PT1539766T
申请日:
2003.05.27
申请国别(地区):
PT
年份:
2017
代理人:
摘要：
The present invention relates to compounds of Formula (I) as antagonists of calcitonin gene-related peptide receptors ("CGRP-receptor"), pharmaceutical compositions comprising them, methods for identifying them, methods of treatment using them and their use in therapy for treatment of neurogenic vasodilation, neurogenic inflammation, migraine and other headaches, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), and other conditions the treatment of which can be effected by the antagonism of CGRP-receptors.
