The present invention relates to stable pharmaceutical compositions which contain polypeptides having at least two antigen-binding domains and are especially suited for subcutaneous administration. The invention provides liquid compositions which minimize the formation of undesired polypeptide aggregates (dimers and/or multimers). The present invention further provides a method for minimizing the aggregation of polypeptides having antigen-binding domains in liquid compositions.本發明是有關於穩定的醫藥組成物,其包含具有至少兩個抗原-結合域的多肽且尤其適於皮下投與。本發明提供液體組成物,其將非所欲多肽團聚體(二聚體及/或多聚體)的形成減至最低。本發明進一步提供一種用以在液體組成物中將具有抗原-結合域的多肽團聚降至最低的方法。
