Attila Balázs;Ádám Demeter;János Csörgei;Csaba Sánta
发明人:
Attila Balázs,János Csörgei,Ádám Demeter,Csaba Sánta
申请号:
US13387783
公开号:
US09221870B2
申请日:
2010.08.05
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to novel crystalline Form II of 17α-acetoxy-21-methoxy-11β-[4-N,N-dimethylaminophenyl]-19-norpregna-4,9-diene-3,20-dione, (also known as CDB-4124), processes for the preparation thereof and pharmaceutical compositions comprising it. Form II can be crystallized from different medium such as esters of C1-C4 alcohols and carboxylic acids, ketones, cyclohexane, acetonitrile, dimethylformamide, dimethyl sulfoxide, water and any mixture thereof.