SYSTEME D'ADMINISTRATION DE MEDICAMENT.

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专利权人:

MERCK SHARP & DOHME B.V.

发明人:

VERHOEVEN, WILLY J. H.,DE GRAAFF, WOUTER

申请号：

CA2931559

公开号：

CA2931559C

申请日:

2014.12.08

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

Described herein is an intra-vaginal drug delivery system comprising (i) a core comprising a first thermoplastic polymer and a first therapeutic agent, wherein the first therapeutic agent is dissolved in the first thermoplastic polymer, and (ii)a skin surrounding the core comprising a second thermoplastic polymer, wherein the first therapeutic agent is less permeable in the second thermoplastic polymer than the first thermoplastic polymer, and a second therapeutic agent in solid form, wherein the second therapeutic agent is loaded in a portion of the skin.

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