The present invention relates to a compound represented by general formula (I) and a stereoisomer or a pharmaceutically acceptable salt, and applications in the preparation of drugs used to prevent and treat cancers. The structure of the compound represented by general formula (I) is shown below, and the definition of A is consistent with that in a specification.本發明涉及一種通式(I)所示化合物及其立體異構體或藥學上可接受的鹽,以及在製備用於預防和治療癌症藥物中的用途,通式(I)化合物的結構如下所示,A的定義與說明書定義一致;