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REMOVAL OF SENESCENCE-ASSOCIATED MACROPHAGES
专利权人:
INC.;EVERON BIOSCIENCES
发明人:
Andrei GUDKOV,Alexander POLINSKY,Vitaly BALAN,Olga CHERNOVA,Brandon M. HALL,Pavel G. KOMAROV,Denis N. KAZYULKIN
申请号:
US16096601
公开号:
US20200123127A1
申请日:
2017.04.25
申请国别(地区):
US
年份:
2020
代理人:
摘要:
In various aspects and embodiments provided are compounds, compositions and methods relating to aging, senescent cells (SCs) and/or senescence associate macrophages (SAMs). In certain aspects and embodiments provided are compounds and compositions that selectively kill or reprogram senescent cells (SCs) and or senescence associate macrophages (SAMs) and associated methods. In some embodiments, the compounds compositions and methods treat or reverse aging organism Normal tissue and/or age-related diseases.
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