VACCINS D'OMV (VÉSICULE DE MEMBRANE EXTERNE)

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专利权人:

GlaxoSmithKline Biologicals SA

发明人:

申请号：

EP11775837.5

公开号：

EP2580314B1

申请日:

2011.06.10

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The invention is in the field of outer membrane vesicles (OMV) and their uses. More particularly the present invention provides OMV obtained from a bacterium being an ompA mutant and/or a mutant in one or more components of the Tol-Pal complex and presenting a heterologous antigen on its surface. The heterologous antigen is selected from the group consisting of Chlamydia trachomatis CT823, CT681, CT372, CT443, CT043, CT733, CT279, CT601 and CT153 for the treatment, prevention or diagnosis of Chlamydia infection.

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