#$%^&*AU2017202137A120181018.pdf#####ABSTRACT A method (100) and system (1) for diagnosing reflux disease in an individual (3). The method (100) comprises: administering (110) an oral dose (17) of tracer in to the individual； capturing )120), with a single photon emission computed tomography (SPECT) scanner (5), data representative of multiple image frames (21) of the individual in areas of interest (23) that include the pharynx (25) and oesophagus (27), wherein the data representative of multiple image frames (21) are captured over time after administration of the oral dose； and determining (130) one or more trend(s) in tracer activity over time in the areas of interest (23) based on the data representative of multiple image frames (21),wherein the trend(s) in tracer activity over time is indicative of a reflux disease.2/14 5o Oral dose 17 Individual 3 7/9 Administer an oral dose of tracer to the individual - -110 Capturing, with a SPECT/ CT scanner, data representative of multiple images of the individual in areas of interest that includes the pharynx and oesophagus, wherein the data representative of 120 -multiple images are captured over time after administration of the oral dose Send data representative Receive data representative 124 of the multiple images of the multiple images 126 Determine one or more trend(s) in tracer activity over time in the areas of interest based on the multiple images, wherein each image has a sampling time of greater than 5 seconds and less than or 100 equal to 60 seconds, wherein 130 -'the individual is classified as having GERD based on the trend in tracer activity over time. Fig. 2
