Albert Claude Boccara;Fabrice Harms;Bertrand Le Conte Chrestien De Poly
发明人:
Albert Claude Boccara,Fabrice Harms,Bertrand Le Conte Chrestien De Poly
申请号：
US13822852
公开号：
US09185357B2
申请日:
2011.09.19
申请国别(地区):
US
年份:
2015
代理人:
摘要：
According to a first aspect, the invention relates to a multimodal optical sectioning microscope (200, 400, 600) for full-field imaging of a volumic and scattering sample comprising: —a full-field OCT system for providing an image of a first section in depth of the sample comprising an illumination sub-system (201, 401, 601) and a full-field imaging interferometer with a detection sub system (208, 408, 608) and an optical conjugation device for optically conjugating the sample and said detection sub system, wherein said optical conjugation device comprises a microscope objective (203, 403, 603), —a supplementary full-field optical sectioning imaging system for providing a fluorescent image of a second section in depth of said sample comprising a structured illumination microscope with an illumination sub system (623), means (421, 422) for generating at the focal plane of said microscope objective of said full-field imaging interferometer a variable spatial pattern illumination and a detection sub system (624), optically conjugated with said focal plane of the microscope objective.
