FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)
发明人:
GOMIS, ROGER,PLANET, EVARIST
申请号:
CA2875918
公开号:
CA2875918A1
申请日:
2013.06.06
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention relates to a method for the diagnosis or the prognosis of metastasis in lung cancer which comprises determining if the c-MAF gene is amplified in a primary tumor sample. Likewise, the invention also relates to a method for the diagnosis or the prognosis of metastasis in lung cancer, as well as to a method for determining the tendency to develop bone metastasis with respect to metastasis in other organs, which comprise determining the c-MAF gene expression level. Finally, the invention relates to the use of a c-MAF inhibitor as therapeutic target for treating the lung cancer.