Hearing loss model animal and its use

• 收藏
• 分享

专利权人:

国立大学法人名古屋大学

发明人:

加藤 昌志,大神 信孝,高橋 雅英,浅井 直也,時々輪 真由美

申请号：

JP2009053481

公开号：

JP5531198B2

申请日:

2009.03.06

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

<；P>；PROBLEM TO BE SOLVED: To provide a model animal showing a hearing loss phenotype and a use thereof in order to achieve means for preventing or treating hearing loss or tinnitus. <；P>；SOLUTION: A rodent gene-modified animal shows a phenotype of aging hearing loss by lesion of one allele Ret gene. A method for screening a substance effective for preventing or treating ageing hearing loss or noise deafness includes using the rodent gene-modified animal. Meanwhile, the rodent gene-modified animal shows a phenotype of congenital deafness by lesion of both allele Ret genes. A method for screening a substance effective for treating congenital deafness includes using the rodent gene-modified animal. <；P>；COPYRIGHT: (C)2010,JPO&INPIT

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/