The invention relates to a sterile preparation which can be implanted on or in organic tissues, comprising: a natural or modified globin material which is insoluble at physiological pH and/or a material obtainable from globin which has been modified to be soluble at physiological pH, the said materials being biocompatible and biodegradable in the organism an agent selected from natural or synthetic polymeric adhesive agents, polymeric tissue enhancement or filling agents, more particularly an agent based on crosslinked hyaluronic acid or on polylactic acid, and a polymeric wound cicatrisation agent, specifically oxidized cellulose with the provisos that, if the preparation comprises the said material obtainable from globin modified so as to be at least partly soluble, the said polymeric adhesive agent, if present, is not hyaluronic acid or carboxymethylcellulose and the said polymeric enhancement or filling agent, if present, is an agent based on crosslinked hyaluronic acid, and that, if the preparation comprises oxidized cellulose, the latter is present in a proportion greater than that of the said globin material, which in that case is a natural or modified globin material which is insoluble at physiological pH and the use of this preparation, more particularly for filling or cicatrisation.Linvention concerne une préparation stérile implantable sur ou dans des tissus organiques comprenant un matériau de globine naturelle ou modifiée et insoluble au pH physiologique et/ou un matériau susceptible dêtre obtenu à partie de globine modifiée pour être soluble à pH physiologique, lesdits matériaux étant biocompatibles et biodégradables dans lorganisme un agent choisi parmi les agents polymériques adhésifs, synthétiques ou naturels, les agents polymériques de comblement ou augmentation tissulaire, notamment un agent à base dacide hyaluronique réticulé, dacide polylactique et un agent polymérique de cicatrisation de plaies, à savoir la cellulose oxydée sous la réserver
