The present invention relates to a connection arrangementand a method of assembly, for providing a substantially tamper resistantconnection with at least a first medical device. The connection arrangement(1) having a centre axis (A), the connection arrangement (1) comprises；a first connection member (21, 161, 521, 621) for connection to thefirst medical device by means of a rotational motion in a first direction,and a body (60, 120, 504, 603). Additionally the first connection member(21, 161, 521, 621) and the body (60, 120, 504, 603) are connected directlyor indirectly together via at least one designated ruptureable retainingmember (41, 141, 541, 641), the designated ruptureable retaining member(41, 141, 541, 641) is arranged to rupture at a predetermined breakingforce, wherein the first connection member (21, 161, 521, 621), and therebythe first medical device after assembly, can be displaced with respect tothe body (60, 120, 504, 603) after rupture. The present invention providesfor a substantially tamper safe connection arrangement which disablesaccidentssuch as wrongly disengage a connected medical device. A saferhandling is provided for the involved user(s).
