HANDY, ERIK S.,IVKOV, ROBERT,ELLIS-BUSBY, DIANE,FOREMAN, ALLAN,BRAUNHUT, SUSAN J.,GWOST, DOUGLAS U.,ARDMAN, BLAIR
申请号:
CA2453676
公开号:
CA2453676C
申请日:
2002.07.25
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
Disclosed are therapeutic methods for the treatment of diseased, disease-causing, or undesirable tissue or material that involve the administration ofa thermotherpeutic magnetic composition, which contains single-domain magneticparticles attached to a target-specific ligand, to a patient and theapplication of an alternating magnetic field to inductively heat thethermotherapeutic magnetic composition. Also disclosed are methods foradministration of the thermotherapeutic magnetic composition. Thesetherapeutic methods may be used where the predetermined target is associatedwith a disease, such as cancer, diseases of the immune system, pathogen-bornediseases, obesity, hormone-related diseases, Alzheimer's disease, diseaseprecursor, and undesirable materials, such as undesirable adipose tissue,reactions to organ transplants, HIV infected cells, polypeptides receptors,blood clots, and low density lipoproteins.