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2’-chloro nucleoside analogs for hcv infection
专利权人:
IDENIX PHARMACEUTICALS LLC;UNIVERSITE DE MONTPELLIER;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
发明人:
Mayes, Benjamin Alexander,Moussa, Adel M.,Gosselin, Gilles,Parsy, Christophe Claude,Alexandre, Francois-Rene,Rahali, Houcine,Griffon, Jean-François,Surleraux, Dominique,Dousson, Cyril B.,Pierra, Clair
申请号:
NZ70698513
公开号:
NZ706985A
申请日:
2013.10.07
申请国别(地区):
NZ
年份:
2018
代理人:
摘要:
Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are 2’-chloro nucleosides according to Formula 2001: (2001); or a pharmaceutically acceptable salt, solvate, stereoisomeric form, tautomeric form or polymorphic form thereof, wherein B, Z and PD are as described herein.
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