An insertion mechanism (200 2200) and methods of assembly and operation of a drag pump (1) may include an insertion mechanism housing (202 2202) a housing cap (203) a manifold guide (220 2220) an insertion biasing member (210 2210) initially held in an energized state a retraction biasing member (216 2216) connected to a hub (212 2212) connected to a proximal end of a needle (214 2214) and optionally a clip retainer (219 2219). The retraction biasing member is held initially in an energized state between the hub and manifold guide. A manifold has a manifold body (240B 2240B) and one or more septa (230A 230B 2230A 2230B) defining a manifold header (242 2242). The retraction biasing member may be held initially in an energized state between the hub and the clip retainer. The needle is advanced by the insertion biasing member(s) from the initial configuration to an administration configuration opening a fluid pathway from the manifold header to the target. The drug delivery pump may include an activation mechanism (14) a dreive mechanism (100) a fluid pathway connection (300) and the insertion mechanism (200).
