Disclosed devices for intranasal administration of medicament to a patient can comprise a hand-held unit comprising a gripping portion for being held by an operator, a spray head having a spray apparatus and a nozzle, a control unit coupled to the hand-held unit via at least one connecting tube, and one or more containers for holding medicaments. The at least one connecting tube can be flexible enough to enable easy maneuvering of the hand-held unit and rigid enough to prevent widening of the tube due to inner pressure when medicaments pass from the containers to the hand-held unit.