CHRISTINA MCLAUGHLIN,JACQUES N6ASSTRÖM,JAN OLOF KARLSSON,KARL REINEKE,MICHAEL HALL,ROLF ANDERSSON,SVEN JACOBSSON,TINO KURZ
申请号:
BR112014016497
公开号:
BR112014016497A2
申请日:
2012.12.04
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
A mixed metal complex of a compound of Formula I, or a salt thereof, wherein the mixed metals comprise a Group III-XII transition metal and a Group II metal: wherein X, R1, R2, R3, and R4 are as defined herein, is produced in a one step crystallization from a solution of the Group III-XII transition metal, the Group II metal, and a compound of Formula I. Methods for treatment of a pathological condition in a patient, for example, a pathological condition caused by the presence of oxygen-derived free radicals, comprise administering the mixed metal complex to the patient.