Combination medicament comprising IL-12 and an agent for blockade of T-cell inhibitory molecules for tumour therapy

• 收藏
• 分享

专利权人:

Universitat Zurich Prorektorat MNW

发明人:

Becher, Burkhard,Vom Berg, Johannes

申请号：

AU2012322999

公开号：

AU2012322999A1

申请日:

2012.10.10

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

The invention relates to a combination medicament for treatment of malignant neoplastic disease. The combination medicament comprises an IL-12 polypeptide having a biological activity of IL-12 or a nucleic acid expression vector comprising a sequence encoding such IL-12 polypeptide, and a non-agonist CTLA-4 ligand or non-agonist PD-1 ligand, particularly an anti-CTLA-4 or anti-PD-1 immunoglobulin G.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/