COMBINATION MEDICAMENT COMPRISING IL-12 AND AN AGENT FOR BLOCKADE OF T-CELL INHIBITORY MOLECULES FOR TUMOUR THERAPY

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专利权人:

发明人:

申请号：

EP12780684.2

公开号：

EP2766035A1

申请日:

2012.10.10

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

The invention relates to a combination medicament for treatment of malignant neoplastic disease. The combination medicament comprises an IL-12 polypeptide having a biological activity of IL-12 or a nucleic acid expression vector comprising a sequence encoding such IL-12 polypeptide, and a non-agonist CTLA-4 ligand or non-agonist PD-1 ligand, particularly an anti-CTLA-4 or anti-PD-1 immunoglobulin G.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/