Paul Parren,Joost J. Neijssen,Aran Frank Labrijn,Janine Schuurman,Tom Vink,Jan Van De Winkel,Stefan Loverix,Ignace Lasters
申请号：
US13146297
公开号：
US20120020952A1
申请日:
2010.01.26
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to a method for producing a mixture comprising two or more different antibodies in a single recombinant host cell. In one embodiment, a mixture of different monovalent antibodies is produced. In another embodiment, a mixture of monovalent and bivalent antibodies is produced. The invention also relates to mixtures of antibodies obtainable by the method of the invention and to light chain sequences that are particularly useful in the method of the invention.
