HILLE THOMAS,HILLE THOMAS,HORSTMANN MICHAEL,HORSTMANN MICHAEL,MÜLLER WALTER,MÜLLER WALTER
申请号：
PL07846537
公开号：
PL2094249T3
申请日:
2007.11.07
申请国别(地区):
PL
年份:
2017
代理人:
摘要：
The therapeutic system has an active substance impermeable rear layer (1), a detention adhesive, and a matrix layer (2) containing an active substance buprenorphine and carboxylic acid i.e. levulinic acid, and a detachable protection layer (3). The matrix layer is formed on the basis of amine-resistant dimethyl polysiloxane or polyisobutylene, where the matrix layer dissolves the buprenorphine in the carboxylic acid. A solution in a form of droplets is dispersed in the matrix layer, which stays in diffusible contact with a polyacrylate layer.
