MICHAEL HORSTMANN;THOMAS HILLE;WALTER MULLER;LTS LOHMANN THERAPIE-SYSTEME AG
发明人:
MICHAEL HORSTMANN,WALTER MULLER,THOMAS HILLE
申请号：
IL19874309
公开号：
IL198743A
申请日:
2009.05.14
申请国别(地区):
IL
年份:
2016
代理人:
摘要：
The therapeutic system has an active substance impermeable rear layer (1), a detention adhesive, and a matrix layer (2) containing an active substance buprenorphine and carboxylic acid i.e. levulinic acid, and a detachable protection layer (3). The matrix layer is formed on the basis of amine-resistant dimethyl polysiloxane or polyisobutylene, where the matrix layer dissolves the buprenorphine in the carboxylic acid. A solution in a form of droplets is dispersed in the matrix layer, which stays in diffusible contact with a polyacrylate layer.
