PROBLEM TO BE SOLVED: To provide an apparatus for preparing a drug which prevents only medical liquid in a prefilled syringe from being administered and facilitates the preparing work of the syringe that sucks a prepared drug.SOLUTION: The apparatus 1 for preparing the drug includes the prefilled syringe 3 including an outer cylinder 10 and a cap 30, a drug container 4, and an adapter 2. The adapter includes an adapter body 20 and a puncture appliance 7 which is movable in the adapter body. The puncture appliance includes a mounting part capable of mounting the cap of the syringe, an engaging part 73a at the puncture appliance side, and a hollow needle 71. The adapter body includes a guide path for guiding the protruding part of the puncture appliance, and the guide path includes a guide path 86a in a circumferential direction, a guide path 85a in an axial direction continuous with the guide path in the circumferential direction, a protrusion 88a for restricting the rotation of the puncture appliance arranged at the guide path in the circumferential direction, and a protrusion 89a for restricting the movement of the puncture appliance arranged at the guide path in the axial direction.COPYRIGHT: (C)2013,JPO&INPIT【課題】プレフィルドシリンジ内の医療用液体のみが投与されることがなく、調製済み薬剤を吸引したシリンジの準備作業が容易である薬剤調製用具を提案する。【解決手段】薬剤調製用具1は、外筒10、キャップ30を備えるプレフィルドシリンジ3と、薬剤容器4と、アダプタ2とを備える。アダプタは、アダプタ本体20と、アダプタ本体内を移動可能な穿刺具7を備える。穿刺具は、シリンジのキャップを装着可能な装着部と穿刺具側係合部73aと、中空針71を備える。アダプタ本体は、穿刺具の突出部を誘導する誘導路を備え、誘導路は、周方向誘導路86a、周方向誘導路と連続する軸方向誘導路85a、周方向誘導路に設けられた穿刺具回転規制用突起88a、軸方向誘導路に設けたれた穿刺具移動規制用突起89aを備えている。【選択図】図1