ANTIBODIES SPECIFIC FOR HYPERPHOSPHORYLATED TAU AND METHODS OF USE THEREOF.

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专利权人:

H. LUNDBECK A/S

发明人:

ASUNI, Ayodeji Abdur-Rasheed,CHRISTENSEN, Søren,DAECHSEL, Justus,DAVID, Laurent,HELBO, Lone,JENSEN, Thomas,JUHL, Karsten,KJÆRGAARD, Kristian,MARIGO, Mauro,PEDERSEN, Jan,PEDERSEN, Lars,ROSENQVIST, Nina

申请号：

TN2018000419

公开号：

TN2018000419A1

申请日:

2017.07.07

申请国别(地区):

TN

年份:

2020

代理人:

摘要：

The present invention relates to a class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396 with improved affinity, as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and other tauopathies.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/