ALLEN, JOHN GORDON,BRINER, KARIN,COHEN, MICHAEL PHILIP,GALKA, CHRISTOPHER STANLEY,HELLMAN, SARAH LYNNE,MARTINEZ-GRAU, MARIA ANGELES,REINHARD, MATTHEW ROBERT,RODRIGUEZ, MICHAEL JOHN,ROTHHAAR, ROGER RYA
申请号:
CA2556390
公开号:
CA2556390C
申请日:
2005.02.18
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention provides 6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines of Formula I as selective 5-HT2C receptor agonists for thetreatment of 5-HT2C associated disorders including obesity,obsessive/compulsive disorder, depression, and anxiety: I where: R6 is -C=C-R10, -O-R12, -S-R14, or -NR24R25; and other substituents are asdefined in the specification.