ALLEN, JOHN GORDON,BRINER, KARIN,CAMP, ANNE MARIE,CASES-THOMAS, MANUEL JAVIER,HOYING, RICHARD CHARLES,MARTINEZ-GRAU, MARIA ANGELES,MAZANETZ, MICHAEL PHILIP,POKROVSKAIA, NATALIA,RATHMELL, RICHARD EDMUN
申请号：
CA2619287
公开号：
CA2619287C
申请日:
2006.09.01
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention provides 6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines of Formula (I) as selective 5-HT2C receptor agonists for thetreatment of 5-HT2C associated disorders including obesity,obsessive/compulsive disorder, depression, and anxiety: where R6 is -C.ident.C-R10, -CH=CR11R11' , or -(C0-C8)alkyl-Ar2 optionally substituted on the alkylmoiety with 1 to 6 fluoro substituents and other substituents are as definedin the specification.
