CHUNG, YUH SHAN,锺玉山,鍾玉山,SIU, MA LI,司玛莉,司瑪莉,LAI, TZUNG HSIEN,赖宗贤,賴宗賢,YEH, SZU CHIEN,叶思见,葉思見
申请号：
TW103145524
公开号：
TW201524513A
申请日:
2014.12.25
申请国别(地区):
TW
年份:
2015
代理人:
摘要：
An extract of Graptopetalum paraguayense prepared by a method that includes: extracting a Graptopetalum paraguayense (GP) starting material with an alcoholic solvent to produce an alcoholic extract and a residue； separating the residue from the alcoholic extract； extracting the residue with an aqueous dimethyl sulfoxide (DMSO) solvent to produce a DMSO extract； subjecting the DMSO extract to ultrafiltration using a filter having a selected molecular weight cutoff； drying a fraction retained by the filter to obtain the extract of Graptopetalum paraguayense. Uses of an extract of Graptopetalum paraguayense for the treatment or prevention of liver fibrosis, hepatic cirrhosis, liver cancer, recurrence of liver fibrosis after surgery, or recurrence of liver cancer after surgery.本發明係關於一種藉由包括以下之方法製備的石蓮花(Graptopetalum paraguayense)萃取物：用酒精溶劑萃取石蓮花(GP)起始物質，產生酒精萃取物及殘餘物；使該殘餘物與該酒精萃取物分離；用二申亞碸(DMSO)水溶液溶劑萃取該殘餘物，產生DMSO萃取物；該DMSO萃取物使用具有選定分子量截斷值之過濾器進行超過濾；乾燥由該過濾器截留的級分，獲得該石蓮花萃取物。本發明係關於石蓮花萃取物之用途，其用於治療或預防肝纖維化、肝臟硬化、肝癌、術後肝纖維化復發或術後肝癌復發。
