The compound of formula (I) or (II) (R1And R2Or R11And R12Is a hydroxyl group, the other is a hydrogen atom or a fluorine atom R3, R4, R13Represents a hydrogen atom or a fluorine atom-represents a single bond or a double bond R5, R6, R15, R16Represents a hydrogen atom, an alkyl group, or a fluorine atom R7, R17Is-CH2-OR8Or-CH2-OR18Etc R8, R18Is a hydrogen atom or the like, or R6, R16Or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof.式(I)又は(II)(R1及びR2又はR11及びR12はいずれか一方が水酸基、他方は水素原子又はフッ素原子;R3、R4、R13は水素原子又はフッ素原子;----は単結合又は二重結合;R5、R6、R15、R16は水素原子、アルキル基、又はフッ素原子;R7、R17は-CH2-OR8又は-CH2-OR18など;R8、R18は水素原子など、又はR6、R16と結合して単結合を示す)で表される化合物を有効成分として含むカスパーゼ1活性化に起因する慢性炎症や自己炎症性疾患などの疾患の予防・治療のための医薬。
