Patrick S. Stayton,Allan S. Hoffman,Anthony Convertine,Craig L. Duvall,Robert Overell,Paul Johnson
申请号:
US14173730
公开号:
US20140228516A1
申请日:
2014.02.05
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A composition for delivering an agent to a cell, comprising a bispecific affinity reagent and a pH-responsive, membrane destabilizing polymer. The bispecific affinity reagent may include a first affinity reagent covalently linked to a second affinity reagent, wherein the first affinity reagent binds to a molecule on the surface of a cell, and the second affinity reagent binds to an intracellular target.