作為前列腺素D2受體拮抗劑之經取代嘧啶類农业专利-农业专业知识服务系统

发明人:: HARRIS, KEITH JOHN,哈瑞斯　凯思约翰,哈瑞斯　凱思約翰,AGUIAR, JOACY C.,艾圭尔　乔艾西,艾圭爾　喬艾西,SHUM, PATRICK WAI-KWOK,沈　伟国,沈　偉國,ZHAO, ZHICHENG,赵志城,趙志城,POLI, GREGORY BERNARD,波利　葛列格里柏纳德,波利　葛列格里柏納德,STOKLOSA, GREGORY,斯托克罗莎　葛列格里,斯,哈瑞斯凯思约翰,哈瑞斯凱思約翰,艾圭尔乔艾西,艾圭爾喬艾西,沈伟国,沈偉國,波利葛列格里柏纳德,波利葛列格里柏納德,斯托克罗莎葛列格里

摘要：: The present invention is directed to a substituted pyrimidine compound of formula (I)or an enantiomer thereof, or a prodrug or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising such a compound. The invention also includes a method of treatment of a patient by the administration of a pharmaceutically effective amount of such a compound.本發明係針對一種式(I)之經取代的嘧啶化合物：或其對映異構體，或前體藥物或其藥學上可接受的鹽，或一種包含此種化合物的醫藥組成物。本發明還包括一個藉由投與藥學上有效量的此種化合物來治療患者的方法。