A SUBSTITUTED PYRIMIDINE AS A PROSTAGLANDIN D2 RECEPTOR ANTAGONIST农业专利-农业学术服务平台

发明人:: HARRIS, KEITH JOHN,哈瑞斯凯思,哈瑞斯凱思,AGUIAR, JOACY C.,艾圭尔乔艾西,艾圭爾喬艾西,SHUM, PATRICK WAI-KWOK,沈伟国,沈偉國,ZHAO, ZHICHENG,赵志城,趙志城,POLI, GREGORY BERNARD,波利葛高利,波利葛高利,STOKLOSA, GREGORY,史托罗沙葛高利,史托羅沙葛高利,CHOI-S

摘要：: The present invention is directed to a 2,6-substituted-4-monosubstitutedamino-pyrimidine compound of formula (I)or an enantiomer thereof, or an ester prodrug or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising such a compound. The invention also includes a method of treatment of a patient by the administration of a pharmaceutically effective amount of such a compound.本發明係針對一種結構式為(I)的2,6-取代-4-單取代胺基嘧啶化合物或其對映異構體、或酯類前藥或其藥學上可接受的鹽,或一種包含此化合物的醫藥組合物。本發明還包括透過施用療效量的此種化合物來治療患者的方法。