Gale SMITH,Ye LIU,Jing-Hui TIAN,Michael J. MASSARE,Sarathi BODDAPATI,Erica SHANE,Cynthia OLIVER,Gregory GLENN
申请号:
US15819962
公开号:
US20180133308A1
申请日:
2017.11.21
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Disclosed herein are nanoparticles suitable for use in vaccines. The nanoparticles present antigens from pathogens surrounded to and associated with a detergent core resulting in enhanced stability and good immunogenicity. Dosages, formulations, and methods for preparing the vaccines and nanoparticles are also disclosed.