Gale SMITH,Ye Liu,Jing-Hui TIAN,Michael J. MASSARE,Sarathi BODDAPATI,Erica SHANE,Cynthia Oliver,Gregory GLENN
申请号:
US15257436
公开号:
US20170202948A1
申请日:
2016.09.06
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Disclosed herein are nanoparticles suitable for use in vaccines. The nanoparticles present antigens from pathogens surrounded to and associated with a detergent core resulting in enhanced stability and good immunogenicity. Dosages, formulations, and methods for preparing the vaccines and nanoparticles are also disclosed.