Adriana Ingrid Velter,Daniel Oehlrich,Didier Jean-Claude Berthelot,François Paul Bischoff,Frederik Jan Rita Rombouts,Garrett Berlond Minne,Henricus Jacobus Maria Gijsen,Michel Anna Jozef de Cleyn,Mich
申请号：
BR112012000915
公开号：
BR112012000915A2
申请日:
2010.07.13
申请国别(地区):
BR
年份:
2019
代理人:
摘要：
The present invention is concerned with novel substituted triazole and imidazole derivatives of Formula (I) wherein R1, R2, A1, A2, A3, A4, X, and Het1 have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
