Tongfei Wu,Henricus Jacobus Maria Gijsen,Frederik Jan Rita Rombouts,François Paul Bischoff,Didier Jean-Claude Berthelot,Daniel Oehlrich,Michel Anna Jozef De Cleyn,Serge Maria Aloysius Pieters,Garrett
申请号：
US13382659
公开号：
US20120135981A1
申请日:
2010.07.13
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention is concerned with novel substituted triazole and imidazole derivatives of Formula (I)wherein R1, R2, A1, A2, A3, A4, X, and Het1 have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
