A removable artificial tooth assembly detachably connects with human oral cavity is disclosed. The removable artificial tooth assembly includes an appearance unit and a support base. The support base is adapted to be attached to the oral mucosa of the alveolar part and the palatal portion within the human oral cavity. The appearance unit detachably connects with the support base. The appearance unit has artificial tooth for the user to chew. The peripheral area of the support base is more flexible than the central area of thereof, such that the peripheral area of the support base remains attached to the oral mucosa while the oral cavity exercises. Skirt enclosure can thus be ensured. The support base further includes an one-way valve to increase negative pressure effect while the oral cavity is exercising under the circumstances of skirt enclosure. Support base is thus less likely to be loose. Therefore, the removable artificial tooth assembly of the present invention can have a better user experience.一種組合式活動假牙,適於配戴於人體口腔,該組合式活動假牙包括外觀件及支撐基座,支撐基座適於貼附人體口腔無牙齒槽部及腭部上的口腔黏膜,外觀件可分離地組合於支撐基座,外觀件具有人工假牙以供使用者咀嚼使用,其中支撐基座的周緣區域相比於中央區域具有較高的可撓性,使支撐基座能於口腔運動時維持周緣區域與口腔黏膜的密合度,保持邊緣封閉,另支撐基座設有單向排氣設備,能在邊緣封閉的情況下,強化口腔運動狀態下的負壓效應,不易鬆脫,而使本發明的組合式活動假牙具有良好的使用效果。y‧‧‧咬合方向10‧‧‧上顎之外觀件11‧‧‧基底黏膜面111‧‧‧粗糙邊緣12‧‧‧嵌槽13‧‧‧開孔14‧‧‧人工假牙15‧‧‧齒槽基底20‧‧‧第一支撐基座22‧‧‧第二接觸面233‧‧‧支座234‧‧‧啟動柱24‧‧‧緩衝護墊243‧‧‧排氣通道30‧‧‧下顎之外觀件33‧‧‧開孔34‧‧‧人工假牙35‧‧‧齒槽基底40‧‧‧第二支撐基座41‧‧‧第一接觸面43‧‧‧金屬支架432‧‧‧支架主幹433‧‧‧支座434‧‧‧啟動柱44‧‧‧緩衝護墊