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NANOTUBE TRANS-MEMBRANE CHANNELS MIMICKING BIOLOGICAL PORINS
专利权人:
Vadim FROLOV;LAWRENCE LIVERMORE NATIONAL SECURITY, LLC;Jianfei Zhang;UNIVERSIDAD DEL PAÍS VASCO;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人:
Aleksandr Noy,Jia Geng,Jianfei Zhang,Vadim Frolov
申请号:
US15503983
公开号:
US20170304447A1
申请日:
2015.10.05
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Provided herein is a nanopore structure, which in one aspect is a “carbon nanotube porin”, that comprises a short nanotube with an associated lipid coating. Also disclosed are compositions and methods enabling the preparation of such nanotube/lipid complexes. Further disclosed is a method for therapeutics delivery that involves a drug delivery agent comprising a liposome with a NT loaded with a therapeutic agent, introducing the therapeutic agent into a cell or a tissue or an organism; and subsequent release of the therapeutic agents into a cell.
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