COMPOSITION PHARMACEUTIQUE POUR INHIBER LA CROISSANCE DE CELLULES SOUCHES DU CANCER, CONTENANT UN INHIBITEUR DE L'ALDÉHYDE ET UN COMPOSÉ À BASE DE BIGUANIDE
Industry-Academic Cooperation Foundation, Yonsei University;National Cancer Center
发明人:
申请号:
EP16746814.9
公开号:
EP3254680A2
申请日:
2016.02.02
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention relates to a pharmaceutical composition for inhibiting growth of cancer stem cells, containing an aldehyde inhibitor and a biguanide-based compound. The pharmaceutical composition according to the present invention contains a combination of an aldehyde inhibitor and a biguanide-based compound, which can effectively inhibit the growth of cancer stem cells such as neurospheres and can also inhibit the proliferation, invasion and metastasis of cancer cells, thereby preventing and/or treating cancer such as brain cancer.