COMPOSITION PHARMACEUTIQUE POUR INHIBER LA CROISSANCE DE CELLULES SOUCHES DU CANCER, CONTENANT UN INHIBITEUR DE L'ALDÉHYDE ET UN COMPOSÉ À BASE DE BIGUANIDE
National Cancer Center; Yonsei University;Industry-Academic Cooperation Foundation, Yonsei University;Industry-Academic Cooperation Foundation
发明人:
KANG, Seok Gu,CHANG, Jong Hee,KIM, Eui Hyun,LEE, Ji Hyun,JO, Yun Hee,PARK, Junseong,SHIM, Jin Kyoung,KIM, Soo Youl
申请号：
EP16746814
公开号：
EP3254680A4
申请日:
2016.02.02
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
The present invention relates to a pharmaceutical composition for inhibiting growth of cancer stem cells, containing an aldehyde inhibitor and a biguanide-based compound. The pharmaceutical composition according to the present invention contains a combination of an aldehyde inhibitor and a biguanide-based compound, which can effectively inhibit the growth of cancer stem cells such as neurospheres and can also inhibit the proliferation, invasion and metastasis of cancer cells, thereby preventing and/or treating cancer such as brain cancer.
