A method for formulating a cationic and non-ionic oil in water emulsion, preferably in a cream form, containing growth factors, preferably platelet derived growth factors, specific matrikine peptides, botanicals, emollients, nano-molecules, antioxidants, antiseptics, neuro-peptides, anti-dermatophytics, polysaccharides, sensorial peptides, osmotically driven moisturizers, and siloxane barriers. For application to the feet and other affected parts of the body for the relief of diabetic skin and tissue trauma.
