NON-HUMAN MAMMALIAN MODEL ANIMAL OF EPILEPSY

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专利权人:

发明人:

申请号：

JP20090507755

公开号：

JP2009534051(A)

申请日:

2007.04.24

申请国别(地区):

日本

年份:

2009

代理人:

摘要：

A transgenic non-human animal, such as a mouse, has a genome that include a nucleic acid construct having at least one transcriptional regulatory sequence capable of directing expression in B cells of the animal, wherein the transcriptional regulatory sequence is operably linked to a nucleic acid encoding a miR155 gene product. A method of testing the therapeutic efficacy of an agent in treating or preventing a lymphoproliferative condition includes assessing the effect(s) of the agent on a transgenic non-human animal.

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中国工程科技知识中心

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